Efficacy and Safety of Cerebrolysin as an Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Observational Studies
Afridi A, Sajjad F, Arshad A, Shahid I, Fatima NE, Alam U, Hoti RK, Abdullah M, Khan S, GhanimAl-Badri S, Khan S, Bakkar MA, Saeed A, Ali A, Khan LA, Kamil KA · 2026 · Brain and behavior · PMID 41880098
What does this source report?
Authors report favorable recovery and safety associations, but inconsistent denominators prevent reliable interpretation of the quoted estimates.
- Population and setting
- 2026 review of three observational thrombectomy-adjunct studies
- Evidence type
- Review
- Preparation
- See the original report; formulation details require verification.
- Source language
- English
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Reported outcome denominators conflict with the stated total sample and treatment-group sizes.
- Observational comparisons are vulnerable to confounding; no randomized adjunct effect is established.
- Effect estimates are withheld pending reconciliation with the original cohorts.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Abstract reviewed
Source access and review scope
Indexed citation and abstract reviewed via Europe PMC / PubMed; full methods and risk of bias not comprehensively appraised.
Recorded source-check date: 2026-10-05. This date does not imply a completed systematic review.
Open original source or index record ↗
DOI: 10.1002/brb3.71252
Cite and trace this record
Original source: Afridi A, Sajjad F, Arshad A, Shahid I, Fatima NE, Alam U, Hoti RK, Abdullah M, Khan S, GhanimAl-Badri S, Khan S, Bakkar MA, Saeed A, Ali A, Khan LA, Kamil KA. Efficacy and Safety of Cerebrolysin as an Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Observational Studies Brain and behavior · PMID 41880098 2026.
Molekul research summary: https://molekul.io/research/stroke-41880098. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry