Neuroprotective effect of GK-2, a dipeptide mimetic of nerve growth factor, during experimental focal ischemia in middle cerebral artery basin
Seredenin SB, Silachev DN, Gudasheva TA, Pirogov YA, Isaev NK · 2011 · Bulletin of experimental biology and medicine · PMID 22462051
What does this source report?
GK-2 reduced infarct area and improved neurological tests.
- Population and setting
- Rats with focal cerebral ischemia after middle cerebral artery occlusion
- Evidence type
- Animal / experimental
- Preparation
- See the original report; formulation details require verification.
- Source language
- English
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Animal-only finding; human stroke benefit and safety are unestablished.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Abstract reviewed
Source access and review scope
Indexed citation and abstract reviewed via Europe PMC / PubMed; full methods and risk of bias not comprehensively appraised.
Recorded source-check date: 2026-10-05. This date does not imply a completed systematic review.
Cite and trace this record
Original source: Seredenin SB, Silachev DN, Gudasheva TA, Pirogov YA, Isaev NK. Neuroprotective effect of GK-2, a dipeptide mimetic of nerve growth factor, during experimental focal ischemia in middle cerebral artery basin Bulletin of experimental biology and medicine · PMID 22462051 2011.
Molekul research summary: https://molekul.io/research/stroke-22462051. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry