IPH-AGAA in cultured muscle cells
R. Roitman, J. Lerner, E. Korshun, A. Ilnitskii, N. Pozdnjakova, S. Gorelik, K. Bocharova, T. Olenskaya · 2017 · International Journal of Applied and Fundamental Research, original report
Indexed 2026-11-09.
Related evidence maps: Sports performance ↗
Reported findings and study design
Myogenic differentiation marker expression increased 2.9- and 2.8-fold at 20 and 200 ng/mL in human-derived cells.
Marker expression quantified by immunocytochemistry after exposing cells to peptide concentrations.
Dose, route and schedule
In vitro concentrations of 2, 20 and 200 ng/mL. Selected responses at 20 and 200 ng/mL.
Protocol source ↗ · International Journal of Applied and Fundamental Research, original report
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Myf5 marker | 2.9- and 2.8-fold versus control | 20 and 200 ng/mL, respectively. The rat culture did not show the same differentiation response. |
| p53 expression | 1.6- and 1.5-fold lower | 20 and 200 ng/mL in human-derived cultures. |
| Pax7 and Ki67 | About 1.2-fold changes at selected concentrations | Marker assays do not measure whole-muscle regeneration. |
Cell-culture results cannot establish a clinical dose or athletic benefit. Report alternates IPH and IHP spelling.
Source for the extracted data ↗ · Checked 2026-11-09
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Cell-culture results cannot establish a clinical dose or athletic benefit. Report alternates IPH and IHP spelling.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: International Journal of Applied and Fundamental Research, original report
Review depth: Reported methods, results and evidence limitations
Source access and review scope
International Journal of Applied and Fundamental Research, original report
Recorded source-check date: 2026-11-09. This date does not imply a completed systematic review.
Source type: International Journal of Applied and Fundamental Research, original report
Citation and original source
Original source: R. Roitman, J. Lerner, E. Korshun, A. Ilnitskii, N. Pozdnjakova, S. Gorelik, K. Bocharova, T. Olenskaya. IPH-AGAA in cultured muscle cells International Journal of Applied and Fundamental Research, original report 2017.
Molekul research summary: https://molekul.io/research/roitman-iph-agaa-myocytes-2017. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry