Research libraryMOLEKUL / SOURCE RECORD

POLYNCOR: lipid and liver-enzyme findings with adjunctive Ropren

E. V. Vyshlov, E. I. Tsoy, V. S. Sultanov, V. B. Trusov, V. V. Ryabov · 2018 · Bulletin of Experimental Biology and Medicine. 165(3):319–321

Randomized trialEnglish abstractSource linked

Reported findings and study design

Reported findings and study figures · Original indexed abstract; registry identity cross-checked
MeasureResultComparison, timing and statistics
Statin reduction/discontinuation for raised transaminasesRopren: zero (0%); control: five (33.3%); reported p<0.05.
Cholesterol and ALTReported lower than control after two months, p<0.05; raw concentrations absent.

The subgroup denominator and full safety accounting need the paper. This does not establish fewer cardiovascular events.

Source for the extracted data ↗ · Checked 2026-11-06

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • The reported 0 versus five (33.3%) statin changes do not establish the entire trial denominator.
  • No mortality or cardiovascular-event benefit is established here.
  • Industry affiliations appear among the authors; disclosures need full-text review.
  • The 2021 report shares this program, not independent replication.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Document format: PubMed/Europe PMC abstract and original registry JSON

Review depth: Abstract and registry checked; full paper not recovered

Related-report group: polyncor-nct03122340. Reports in this group are not assumed to be independent trials.

Source access and review scope

Original indexed abstract; registry links this publication to POLYNCOR.

Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.

Source type: Clinical publication from NCT03122340

Open original source or index record ↗

DOI: 10.1007/s10517-018-4159-x

Citation and original source

Original source: E. V. Vyshlov, E. I. Tsoy, V. S. Sultanov, V. B. Trusov, V. V. Ryabov. POLYNCOR: lipid and liver-enzyme findings with adjunctive Ropren Bulletin of Experimental Biology and Medicine. 165(3):319–321 2018.

Molekul research summary: https://molekul.io/research/polyprenols-polyncor-2018. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

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