Cognitive effects of piracetam in adults with memory impairment: A systematic review and meta-analysis
Gouhie FA, Barbosa KO, Cruz ABR, Wellichan MM, Zampolli TM · 2024 · Clinical neurology and neurosurgery 243(). PMID 38878641
What does this source report?
The 2024 meta-analysis did not establish a statistically significant pooled memory benefit: SMD 0.75, 95% CI −0.19 to 1.69; p=0.12; I²=96%.
- Population and setting
- 18 studies; 886 adults with memory impairment
- Evidence type
- Review
- Preparation
- See the original report; formulation details require verification.
- Source language
- English
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Very high heterogeneity limits a single pooled interpretation.
- Clinical memory impairment is not a healthy-operator population; this review is not an additional trial.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Europe PMC indexed citation and abstract checked; complete original methods not appraised.
Recorded source-check date: 2026-09-30. This date does not imply a completed systematic review.
Cite and trace this record
Original source: Gouhie FA, Barbosa KO, Cruz ABR, Wellichan MM, Zampolli TM. Cognitive effects of piracetam in adults with memory impairment: A systematic review and meta-analysis Clinical neurology and neurosurgery 243(). PMID 38878641 2024.
Molekul research summary: https://molekul.io/research/pir-38878641. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry