Clinical efficacy and safety of Picamilon in patients with progressive chronic cerebral ischemia
Danilov AB, Shindryaeva NN, Borodulina IV, Lunegov TD, Kristeleva DA · 2024 · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 124(8). PMID 39269299
What does this source report?
An open cohort reported changes in cognition, sleep questionnaires and vascular measures. No untreated comparator is described; this cannot establish benefit in healthy mariners.
- Population and setting
- 50 stage II patients (5 men, 45 women); 70-day active treatment and 45-day follow-up
- Evidence type
- Uncontrolled human report
- Preparation
- See the original report; formulation details require verification.
- Source language
- Russian; English abstract
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Uncontrolled treatment cohort; expectation, repeated testing and concomitant care can affect outcomes.
- Questionnaire improvement is not evidence about wearable sleep stages.
- Strong similarities to the 2025 stage II group warrant overlap checks before any pooling.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Publisher HTML article
Review depth: Methods and outcomes
Related-report group: picamilon-2024-2025-overlap-unresolved. Reports in this group are not assumed to be independent trials.
Source access and review scope
Publisher methods and outcome descriptions checked; no untreated comparator.
Recorded source-check date: 2026-10-02. This date does not imply a completed systematic review.
Cite and trace this record
Original source: Danilov AB, Shindryaeva NN, Borodulina IV, Lunegov TD, Kristeleva DA. Clinical efficacy and safety of Picamilon in patients with progressive chronic cerebral ischemia Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 124(8). PMID 39269299 2024.
Molekul research summary: https://molekul.io/research/pic-39269299. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry