Integrative assessment of the effectiveness and safety of outpatient use of Picamilon
Danilov AB, Shindryaeva NN, Borodulina IV, Lunegov TD · 2024 · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 124(7). PMID 39113452
What does this source report?
Both active-treatment groups reported cognitive and sleep-questionnaire changes. All 44 completed treatment. Without an inactive comparator, change cannot establish drug efficacy.
- Population and setting
- 44 stage I patients: 23 oral-only and 21 sequential parenteral/oral; 60 days of treatment
- Evidence type
- Randomized trial
- Preparation
- See the original report; formulation details require verification.
- Source language
- Russian; English abstract
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Open comparison of two active schedules; no placebo or untreated group.
- Questionnaire sleep outcomes are not measured sleep stages.
- Possible overlap with the 2025 report remains unresolved; do not sum cohorts.
- Biomarker change does not demonstrate fewer cardiovascular events.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Publisher HTML article
Review depth: Methods, results and harms narrative
Related-report group: picamilon-2024-2025-overlap-unresolved. Reports in this group are not assumed to be independent trials.
Source access and review scope
Publisher full-text methods, outcome tables and harms narrative checked.
Recorded source-check date: 2026-10-02. This date does not imply a completed systematic review.
Cite and trace this record
Original source: Danilov AB, Shindryaeva NN, Borodulina IV, Lunegov TD. Integrative assessment of the effectiveness and safety of outpatient use of Picamilon Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 124(7). PMID 39113452 2024.
Molekul research summary: https://molekul.io/research/pic-39113452. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry