Phenotropil: antidepressant-use patent — RU2232578C1
В.И. Ахапкина (RU), В.И. Ахапкина, Р.В. Ахапкин (RU), Р.В. Ахапкин, Ю.А. Александровский (RU), Ю.А. Александровский, А.С. Аведисова (RU), А.С. Аведисова, Т.А. Воронина (RU), Т.А. Воронина, В.В. Нестерук (RU), В.В. Нестерук · 2004 · RU2232578C1 · patent family 33157471
Published 2004-07-20.
Reported patent results
Narrative findings; numerical extraction incomplete
The clinical section reports antidepressant activity but does not provide independently transcribed Hamilton score changes.
Depression patent describes 40 adults aged 20–42: 20 Phenotropil and 20 amitriptyline, alongside animal experiments.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Clinical depression scale | Hamilton-scale improvement reported for Phenotropil | Exact baseline/endpoint means, uncertainty and responder counts are not entered |
| Comparator claim | The narrative states activity was not inferior to amitriptyline | No prespecified noninferiority margin or adequate noninferiority analysis established |
A small patent comparison and a narrative claim cannot establish modern comparative depression efficacy, absence of withdrawal or long-term safety.
Source for the extracted data ↗ · Checked 2026-11-06
Patent claims and provenance
Use. The Russian document proposes phenylpiracetam for an antidepressant application.
Patent experimental claims are not a completed modern clinical depression trial.
- Publication
- RU2232578C1 ↗ · 2004-07-20
- Earliest priority / filing
- 2003-04-10 / 2003-04-10
- Original applicant / assignee
- Ахапкина Валентина Ивановна
- Indexed status
- Not shown; official status unverified · checked 2026-11-06
- Patent family
- 33157471 · family publications are related filings, not independent studies.
Original title, inventors and related publications
Substance eliciting antidepressant activity
Inventors: В.И. Ахапкина (RU); В.И. Ахапкина; Р.В. Ахапкин (RU); Р.В. Ахапкин; Ю.А. Александровский (RU); Ю.А. Александровский; А.С. Аведисова (RU); А.С. Аведисова; Т.А. Воронина (RU); Т.А. Воронина; В.В. Нестерук (RU); В.В. Нестерук.
RU2232578C1 · US20060287383A1 · EP1619182B1 · CA2521923C · CY1115549T1 · DK1619182T3 · EA009044B1 · ES2486844T3 · PL1619182T3 · PT1619182E · SI1619182T1 · WO2004089893A1
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Patent experimental claims are not a completed modern clinical depression trial.
- A small patent comparison and a narrative claim cannot establish modern comparative depression efficacy, absence of withdrawal or long-term safety.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-33157471. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: В.И. Ахапкина (RU), В.И. Ахапкина, Р.В. Ахапкин (RU), Р.В. Ахапкин, Ю.А. Александровский (RU), Ю.А. Александровский, А.С. Аведисова (RU), А.С. Аведисова, Т.А. Воронина (RU), Т.А. Воронина, В.В. Нестерук (RU), В.В. Нестерук. Phenotropil: antidepressant-use patent — RU2232578C1 RU2232578C1 · patent family 33157471 2004.
Molekul research summary: https://molekul.io/research/patent-ru2232578c1. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry