RU2049472C1: Cerebrolysat manufacturing from bovine brain tissue — RU2049472C1
A. V. Karyakin, G. S. Vasilyev, V. G. Yusupov, V. N. Melnikov, V. F. Kulagin · 1995 · RU2049472C1 · patent family 20133945
Published 1995-12-10.
Reported patent results
Reported findings
Bovine brain homogenate enzymatic hydrolysis, ethanol precipitation, microfiltration and 5–15 kDa nominal ultrafiltration cutoff.
Two applicant manufacturing examples. No verified comparative clinical data in these examples.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Example 1 · process | 10 kDa cutoff; 200 mL final volume | Starting example used 1 kg brain material and serine endoprotease. |
| Example 2 · process | 15 kDa cutoff; applicant reported matching amino-acid composition | This is the composition comparison stated in the disclosure. |
A membrane cutoff is a process parameter. It does not establish the peptide-size distribution or an identity match to PPK-V.
Source for the extracted data ↗ · Checked 2026-11-09
Patent claims and provenance
Manufacturing. Bovine brain homogenate enzymatic hydrolysis, ethanol precipitation, microfiltration and 5–15 kDa nominal ultrafiltration cutoff.
A membrane cutoff is a process parameter. It does not establish the peptide-size distribution or an identity match to PPK-V.
- Publication
- RU2049472C1 ↗ · 1995-12-10
- Earliest priority / filing
- 1992-12-21 / 1992-12-21
- Original applicant / assignee
- Not established from accessed metadata
- Indexed status
- Not shown; official status unverified · checked 2026-11-09
- Patent family
- 20133945 · family publications are related filings, not independent studies.
Original title, inventors and related publications
Способ получения гидролизата мозговой ткани «церебролизат»
Inventors: A. V. Karyakin; G. S. Vasilyev; V. G. Yusupov; V. N. Melnikov; V. F. Kulagin.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- A membrane cutoff is a process parameter. It does not establish the peptide-size distribution or an identity match to PPK-V.
- A membrane cutoff is a process parameter. It does not establish the peptide-size distribution or an identity match to PPK-V.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-20133945. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-09. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: A. V. Karyakin, G. S. Vasilyev, V. G. Yusupov, V. N. Melnikov, V. F. Kulagin. RU2049472C1: Cerebrolysat manufacturing from bovine brain tissue — RU2049472C1 RU2049472C1 · patent family 20133945 1995.
Molekul research summary: https://molekul.io/research/patent-ru2049472c1. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry