Changes in retinal light sensitivity and morphometry during surgical treatment of primary glaucoma with physiotherapeutic stimulation
Yusef Y, Sheludchenko VM, Korzhavina AV, Kosova DV, Volzhanin AV · 2026 · Vestnik oftalmologii 142(5)
Published 2026-10-16. Indexed 2026-10-19.
Reported findings and study design
After glaucoma surgery, a physiotherapy package including Semax electrophoresis improved visual-field mean deviation from −8.62 ± 1.86 to −4.33 ± 0.98 dB, with benefit maintained through six months. The comparison group received Semax nasal drops and returned to baseline by month three. Structural retinal measures and visual-field index did not differ significantly.
Dose, route and schedule
A two-week course of transcranial magnetic/electrical stimulation, endonasal electrophoresis with Semax 0.1% and heliox (21/79), beginning one month after surgery. Controls received Semax 0.1% nasal drops twice daily for ten days. Study methods, not a personal-use protocol.
Protocol source ↗ · Indexed abstract checked
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Participants | 50 patients; 64 eyes | |
| Visual-field mean deviation | −8.62 ± 1.86 → −7.03 ± 1.36 → −4.33 ± 0.98 dB | Baseline → after surgery → after added physiotherapy · p<0.01 after surgery; p<0.0001 after physiotherapy |
| Persistence | Improvement maintained up to 6 months | Control group returned to baseline by month 3 |
| Retinal structure and visual-field index | No significant differences in VFI, AvgRNFL or GCC |
Both groups received Semax. Magnetic/electrical stimulation, heliox and a different delivery method prevent isolating the contribution of Semax. Eyes and patients are separate denominators; allocation and masking require full-methods appraisal.
Source for the extracted data ↗ · Checked 2026-10-31
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Both groups received Semax. Magnetic/electrical stimulation, heliox and a different delivery method prevent isolating the contribution of Semax. Eyes and patients are separate denominators; allocation and masking require full-methods appraisal.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Indexed abstract checked
Source access and review scope
Primary publication metadata and indexed abstract checked through Europe PMC on 31 October 2026. No unavailable effect sizes inferred. Publisher page confirms online publication 2026-10-16.
Recorded source-check date: 2026-10-31. This date does not imply a completed systematic review.
Source type: Journal publication
Citation and original source
Original source: Yusef Y, Sheludchenko VM, Korzhavina AV, Kosova DV, Volzhanin AV. Changes in retinal light sensitivity and morphometry during surgical treatment of primary glaucoma with physiotherapeutic stimulation Vestnik oftalmologii 142(5) 2026.
Molekul research summary: https://molekul.io/research/oct31-42885627. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry