Noopept stimulates the expression of NGF and BDNF in rat hippocampus
R. U. Ostrovskaya, T. A. Gudasheva, A. P. Zaplina, Ju. V. Vahitova, M. H. Salimgareeva, R. S. Jamidanov, S. B. Seredenin · 2008 · Bull Exp Biol Med. 146(3):334–337
What does this source report?
The investigators measured hippocampal NGF and BDNF expression and found increases under the studied conditions. Cortical responses differed.
- Population and setting
- Rats; acute and repeated administration, regional mRNA measurements
- Evidence type
- Animal / experimental
- Preparation
- See the original report; formulation details require verification.
- Source language
- See original publication
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- mRNA measurements in rats do not establish brain neurotrophin changes in humans.
- This does not demonstrate dementia prevention, occupational protection or lasting cognitive benefit.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed primary-paper record and abstract checked; full methods and risk of bias not appraised.
Recorded source-check date: 2026-09-29. This date does not imply a completed systematic review.
Cite and trace this record
Original source: R. U. Ostrovskaya, T. A. Gudasheva, A. P. Zaplina, Ju. V. Vahitova, M. H. Salimgareeva, R. S. Jamidanov, S. B. Seredenin. Noopept stimulates the expression of NGF and BDNF in rat hippocampus Bull Exp Biol Med. 146(3):334–337 2008.
Molekul research summary: https://molekul.io/research/noopept-ngf-bdnf-2008. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry