Molecular Mechanism Underlying the Action of Substituted Pro-Gly Dipeptide Noopept
Yu. V. Vakhitova et al. · 2016 · Acta Naturae. 8(1); PMID 27099787
What does this source report?
Noopept increased HIF-1 reporter activity in this experimental system. Docking suggested a possible interaction with prolyl hydroxylase 2.
- Population and setting
- HEK293 cell reporter assays, chemical hypoxia mimic and molecular docking
- Evidence type
- In vitro
- Preparation
- See the original report; formulation details require verification.
- Source language
- See original publication
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Docking is a mechanistic proposal, not demonstrated target engagement in humans.
- Cell reporter activity cannot establish protection against heat, hypoxia or occupational injury.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Primary article abstract and indexed full-text discussion checked; no independent replication appraisal.
Recorded source-check date: 2026-09-29. This date does not imply a completed systematic review.
Cite and trace this record
Original source: Yu. V. Vakhitova et al.. Molecular Mechanism Underlying the Action of Substituted Pro-Gly Dipeptide Noopept Acta Naturae. 8(1); PMID 27099787 2016.
Molekul research summary: https://molekul.io/research/noopept-hif-2016. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry