Noopept, apoptosis and tau phosphorylation in an amyloid-exposed cell model
Ostrovskaya RU · 2014 · Journal of Biomedical Science
Reported findings and study design
Differentiated PC12 cells received 10 μM Noopept for 72 hours before exposure to 5 μM amyloid-β(25–35). The tau assay used four independent experiments with three replicate wells.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Tau phosphorylation | Phosphorylation at Ser396 fell with Noopept pretreatment (p=0.0024). | |
| Neurites per cell | 2.44 with pretreatment versus 1.64 with amyloid exposure alone (p=0.0022). |
An acute cell assay cannot establish effects on clinical tau pathology or cognition.
Source for these results ↗ · Reviewed 2026-11-12
For research and education. Consult a qualified clinician for medical advice.
Study limitations and source details
Study limitations
- An acute cell assay cannot establish effects on clinical tau pathology or cognition.
Source access
Original full text checked for selected methods and findings.
Source reviewed 2026-11-12.
Source type: Journal publication
Citation and original source
Original source: Ostrovskaya RU. Noopept, apoptosis and tau phosphorylation in an amyloid-exposed cell model Journal of Biomedical Science 2014.
Molekul research summary: https://molekul.io/research/noopept-amyloid-tau-2014. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry