Anxiolytic Effect of GHK-PGP Peptide and Its Structural Analogues in a Test with Punished Behavior
M. E. Alferova, I. I. Bobyntsev, A. O. Vorvul, A. N. Tenkova · 2025 · Bulletin of Experimental Biology and Medicine 2025 179 575-578
Published 2026-01-09.
Study data at a glance
- Participants or experimental model
- Male Wistar rats; Vogel conflict test.
- Reported results
- GHK alone showed no anxiolytic effect in this test. PGP, GHK-PGP, GHK-P and GHK-GP showed exposure-dependent signals, illustrating that a result in one anxiety-related test does not predict all behavioral outcomes.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Animal findings do not establish human efficacy, a human dose, or long-term safety.
- English version online 9 January 2026, assigned to the September 2025 issue; it is one translated report.
- Same research group as the maze and swim papers; independence and animal-cohort overlap require full-text checking.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Primary indexed or publisher abstract and citation checked; complete methods, tables and risk of bias not appraised.
Recorded source-check date: 2026-11-03. This date does not imply a completed systematic review.
Citation and original source
Original source: M. E. Alferova, I. I. Bobyntsev, A. O. Vorvul, A. N. Tenkova. Anxiolytic Effect of GHK-PGP Peptide and Its Structural Analogues in a Test with Punished Behavior Bulletin of Experimental Biology and Medicine 2025 179 575-578 2025.
Molekul research summary: https://molekul.io/research/ghk-proline-conflict-2026. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry