D-tyrosine adds an anti-melanogenic effect to cosmetic peptides
Jisu Park, Hyejung Jung, Bohee Jang, Hyun-Kuk Song, Inn-Oc Han, Eok-Soo Oh · 2020 · Scientific Reports 2020 10
Published 2020-01-14.
Study data at a glance
- Participants or experimental model
- Human pigment-cell models and murine inflammatory-cell assays; distinct experiments on other peptides in the same paper.
- Reported results
- Terminal D-tyrosine added a melanin-reducing signal to GHK while retaining measured anti-inflammatory activity. Findings for the paper’s pentapeptide-18 skin model cannot all be assigned to GHK-D-Tyr.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Animal findings do not establish human efficacy, a human dose, or long-term safety.
- Laboratory pigmentation findings do not establish clinical skin-lightening benefit or safety.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Original publisher PDF abstract and GHK-specific indexed result passage checked; complete experimental appraisal pending.
Recorded source-check date: 2026-11-03. This date does not imply a completed systematic review.
Citation and original source
Original source: Jisu Park, Hyejung Jung, Bohee Jang, Hyun-Kuk Song, Inn-Oc Han, Eok-Soo Oh. D-tyrosine adds an anti-melanogenic effect to cosmetic peptides Scientific Reports 2020 10 2020.
Molekul research summary: https://molekul.io/research/ghk-dtyr-pigmentation-2020. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry