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Effects of Gly-His-Lys-D-Ala Peptide on Skin Wound Regeneration Processes

K. K. Rakhmetova, E. S. Mishina, I. I. Bobyntsev, A. I. Bezhin, A. O. Vorvul · 2024 · Bulletin of Experimental Biology and Medicine 2024 176 411-416

Published 2024-02-12.

Animal / experimentalEnglish abstractSource linked

Study data at a glance

Participants or experimental model
80 male Wistar rats; histology and morphometry through day 30.
Reported results
The abstract reports more fibroblastic cells and macrophages, fewer granulocytes, and active wound contraction at day 30. This adds tissue-level context to the D-alanine series.

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • Animal findings do not establish human efficacy, a human dose, or long-term safety.
  • English translation of a September 2023 Russian report; the two versions are not separate experiments.
  • Complete methods and possible overlap with the group’s earlier cohorts remain unresolved.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Primary indexed or publisher abstract and citation checked; complete methods, tables and risk of bias not appraised.

Recorded source-check date: 2026-11-03. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1007/s10517-024-06035-w

Citation and original source

Original source: K. K. Rakhmetova, E. S. Mishina, I. I. Bobyntsev, A. I. Bezhin, A. O. Vorvul. Effects of Gly-His-Lys-D-Ala Peptide on Skin Wound Regeneration Processes Bulletin of Experimental Biology and Medicine 2024 176 411-416 2024.

Molekul research summary: https://molekul.io/research/ghk-dala-histology-2024. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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