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Effects of GHK peptide and its structural analogues on dynamics of healing and bacterial contamination of infected wound

Kamila K. Rakhmetova, Igor' I. Bobyntsev, Lyudmila V. Zhilyayeva, Aleksandr I. Bezhin, Anton O. Vorvul' · 2024 · I.P. Pavlov Russian Medical Biological Herald 2024 32 539-548

Published 2024-12-27.

Animal / experimentalRussian source · see review scopeSource linked

Reported findings and study design

150 male Wistar rats; wound-area and healing assessments.

Reported findings and study figures · Original English/Russian publisher abstract, indexed PDF and publisher-deposited metadata checked; complete statistical appraisal pending.
MeasureResultComparison, timing and statistics
GHK-D-Ala wound areaApproximately 93% lower than controlDay 10 · Reported p<0.001
Interval-specific healing rate4.7–5.3-fold higher with GHK-D-AlaRelative to control; not total healing duration · Days 7–10

Animal findings do not establish human efficacy, a human dose, or long-term safety. This is not evidence that GHK-Cu or a GHK-D-Ala copper complex gives the same result. Related reports may share research material; publication counts should not be read as independent replications.

Source for the extracted data ↗ · Checked 2026-11-03

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • Animal findings do not establish human efficacy, a human dose, or long-term safety.
  • This is not evidence that GHK-Cu or a GHK-D-Ala copper complex gives the same result.
  • Related reports may share research material; publication counts should not be read as independent replications.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Original English/Russian publisher abstract, indexed PDF and publisher-deposited metadata checked; complete statistical appraisal pending.

Recorded source-check date: 2026-11-03. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.17816/PAVLOVJ471212

Citation and original source

Original source: Kamila K. Rakhmetova, Igor' I. Bobyntsev, Lyudmila V. Zhilyayeva, Aleksandr I. Bezhin, Anton O. Vorvul'. Effects of GHK peptide and its structural analogues on dynamics of healing and bacterial contamination of infected wound I.P. Pavlov Russian Medical Biological Herald 2024 32 539-548 2024.

Molekul research summary: https://molekul.io/research/ghk-dala-healing-2024. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

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