The GHK-Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways
H. Wen, K. Zhao, X. Luo, J. Pu, Y. Li, Y. Dou, J. He, X. Nie, Y. Ke, W. Zhou · 2026 · Biogerontology. 2026;27:100.
Published 2026-05-05.
Study data at a glance
- Participants or experimental model
- Caenorhabditis elegans; lifespan, stress resistance and mitochondrial/pathway measurements.
- Reported results
- The paper reports longer worm lifespan and changes in mitochondrial function, DAF-16 and SKN-1 signaling. It is a new animal longevity result, without a human longevity endpoint.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Animal findings do not establish human efficacy, a human dose, or long-term safety.
- Complete effect sizes, controls and mechanistic specificity require full-text review.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Primary indexed or publisher abstract and citation checked; complete methods, tables and risk of bias not appraised.
Recorded source-check date: 2026-11-03. This date does not imply a completed systematic review.
Citation and original source
Original source: H. Wen, K. Zhao, X. Luo, J. Pu, Y. Li, Y. Dou, J. He, X. Nie, Y. Ke, W. Zhou. The GHK-Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways Biogerontology. 2026;27:100. 2026.
Molekul research summary: https://molekul.io/research/ghk-cu-worm-aging-2026. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry