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A prospective randomized evaluator-blinded trial of two potential wound healing agents for the treatment of venous stasis ulcers

J. B. Bishop, L. G. Phillips, T. A. Mustoe, A. J. VanderZee, L. Wiersema, D. E. Roach, J. P. Heggers, D. P. Hill Jr, E. L. Taylor, M. C. Robson · 1992 · Journal of Vascular Surgery 1992 16 0251-0257

Randomized trialEnglish abstractSource linked

Reported findings and study design

86 evaluable patients completed a randomized evaluator-blinded venous-ulcer trial.

Reported findings and study figures · Primary indexed or publisher abstract and citation checked; complete methods, tables and risk of bias not appraised.
MeasureResultComparison, timing and statistics
Ulcer-size reductionNo difference between copper-tripeptide cream and vehicleSilver sulfadiazine reduced ulcer size more than either

Completer count is not necessarily the randomized enrollment denominator. A specific formulation and venous-ulcer setting; neither a universal benefit nor a universal lack of effect follows.

Source for the extracted data ↗ · Checked 2026-11-03

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • Completer count is not necessarily the randomized enrollment denominator.
  • A specific formulation and venous-ulcer setting; neither a universal benefit nor a universal lack of effect follows.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Primary indexed or publisher abstract and citation checked; complete methods, tables and risk of bias not appraised.

Recorded source-check date: 2026-11-03. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1067/mva.1992.37086

Citation and original source

Original source: J. B. Bishop, L. G. Phillips, T. A. Mustoe, A. J. VanderZee, L. Wiersema, D. E. Roach, J. P. Heggers, D. P. Hill Jr, E. L. Taylor, M. C. Robson. A prospective randomized evaluator-blinded trial of two potential wound healing agents for the treatment of venous stasis ulcers Journal of Vascular Surgery 1992 16 0251-0257 1992.

Molekul research summary: https://molekul.io/research/ghk-cu-venous-ulcers-1992. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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