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Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin

Timothy R. Miller, Jon D. Wagner, Bret R. Baack, Karl J. Eisbach · 2006 · Archives of Facial Plastic Surgery 2006 8 252-259

Randomized trialEnglish abstractSource linked

Reported findings and study design

13 completers after circumoral CO2 laser resurfacing; randomized treatment and blinded objective evaluation.

Reported findings and study figures · Primary indexed or publisher abstract and citation checked; complete methods, tables and risk of bias not appraised.
MeasureResultComparison, timing and statistics
Objective redness, wrinkles and skin qualityNo significant between-group advantage
Patient-reported overall skin qualityFavored GHK-Cu regimen12 weeks · p=0.04

Very small study and regimen-level comparison; objective and subjective findings differ. Improvement after laser treatment in both groups cannot be attributed to the peptide.

Source for the extracted data ↗ · Checked 2026-11-03

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • Very small study and regimen-level comparison; objective and subjective findings differ.
  • Improvement after laser treatment in both groups cannot be attributed to the peptide.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Primary indexed or publisher abstract and citation checked; complete methods, tables and risk of bias not appraised.

Recorded source-check date: 2026-11-03. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1001/archfaci.8.4.252

Citation and original source

Original source: Timothy R. Miller, Jon D. Wagner, Bret R. Baack, Karl J. Eisbach. Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin Archives of Facial Plastic Surgery 2006 8 252-259 2006.

Molekul research summary: https://molekul.io/research/ghk-cu-laser-2006. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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