Effects of topical copper tripeptide complex on wound healing in an irradiated rat model
N. P. Parker, F. Ardeshirpour, S. C. Schmechel, A. A. D. Lassig · 2013 · Otolaryngology–Head and Neck Surgery. 2013;149(3):384–389.
Reported findings and study design
13 treated and 10 control rats analyzed in an irradiated skin-flap model.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Flap ischemia, vascular and VEGF outcomes | No significant advantage at the study’s adjusted threshold |
Animal findings do not establish human efficacy, a human dose, or long-term safety. Negative findings in a specific radiation-injury model qualify broad wound-repair claims; they do not settle every formulation or indication.
Source for the extracted data ↗ · Checked 2026-11-03
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Animal findings do not establish human efficacy, a human dose, or long-term safety.
- Negative findings in a specific radiation-injury model qualify broad wound-repair claims; they do not settle every formulation or indication.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Primary indexed or publisher abstract and citation checked; complete methods, tables and risk of bias not appraised.
Recorded source-check date: 2026-11-03. This date does not imply a completed systematic review.
Citation and original source
Original source: N. P. Parker, F. Ardeshirpour, S. C. Schmechel, A. A. D. Lassig. Effects of topical copper tripeptide complex on wound healing in an irradiated rat model Otolaryngology–Head and Neck Surgery. 2013;149(3):384–389. 2013.
Molekul research summary: https://molekul.io/research/ghk-cu-irradiated-wounds-2013. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry