Opioid receptor agonist dalargin prevents stress-induced cardiac injury and improves myocardial pump function
B. K. Kurbatov, M. Kilin, A. O. Venichenko, A. A. Boshchenko, S. V. Gusakova, L. N. Maslov · 2026 · Bulletin of Experimental Biology and Medicine. 2026;182(8):129–133.
Study findings
Dalargin reduced serum creatine kinase-MB by 27% relative to stressed controls and partially restored cardiac pump function.
- Population and setting
- Female Wistar rats exposed to 24-hour immobilization
- Evidence type
- Animal / experimental
- Source language
- English
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Animal stress model; this does not establish cardioprotection in people.
- Sample size, masking and full statistical methods require the complete paper.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Primary publisher abstract checked; full methods and tables not appraised.
Recorded source-check date: 2026-10-11. This date does not imply a completed systematic review.
Citation and original source
Original source: B. K. Kurbatov, M. Kilin, A. O. Venichenko, A. A. Boshchenko, S. V. Gusakova, L. N. Maslov. Opioid receptor agonist dalargin prevents stress-induced cardiac injury and improves myocardial pump function Bulletin of Experimental Biology and Medicine. 2026;182(8):129–133. 2026.
Molekul research summary: https://molekul.io/research/dalargin-cardiac-stress-2026. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry