Cerebrotein Hydrolysate-I candidate peptide Pep72
Original CH-1 pharmacokinetic study authors · 2023 · Original indexed publication, PMID 37758480
Indexed 2026-11-09.
Related evidence maps: Military & occupational research ↗
Reported findings and study design
Pep72 had very low measured blood–brain barrier permeability. The authors identified 11 main metabolites, including PGGDL and EPPTVPGGDL.
Screening of candidate peptides, permeability and transporter assays, and metabolite identification in fresh rat plasma and tissues.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Pep72 permeability | Very low in the model used | The peptide was not identified as an efflux transporter substrate. |
| Metabolites | 11 major structures identified | PGGDL and EPPTVPGGDL were prominent products. |
| Exposure details | Study-specific doses require the complete methods | No dosing equivalence to Cortexin or PPK-V. |
Results concern one hydrolysate and its candidate metabolites. Similar molecular mass alone does not support a formulation match.
Source for the extracted data ↗ · Checked 2026-11-09
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Results concern one hydrolysate and its candidate metabolites. Similar molecular mass alone does not support a formulation match.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original indexed publication, PMID 37758480
Review depth: Reported methods, results and evidence limitations
Source access and review scope
Original indexed publication, PMID 37758480
Recorded source-check date: 2026-11-09. This date does not imply a completed systematic review.
Source type: Original indexed publication, PMID 37758480
Citation and original source
Original source: Original CH-1 pharmacokinetic study authors. Cerebrotein Hydrolysate-I candidate peptide Pep72 Original indexed publication, PMID 37758480 2023.
Molekul research summary: https://molekul.io/research/cerebrotein-pep72-2023. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry