Bemitil after surgery for lung abscesses
O. V. Maslova · 2004 · Chelyabinsk State Medical Academy. Dissertation author abstract, 2004.
Reported findings and study design
Reported findings
Of 94 patients, 46 received conservative care and 48 had surgery. Standard postoperative care was antibacterial and detoxification therapy (n=25). The adjunct arm (n=23) received the same care plus Bemitil 250 mg twice daily for 7 days. The author abstract does not state the route. Blood was assessed at admission and on hospital days 14–19, corresponding to postoperative days 7–10.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Complete recovery or improvement | 82.6% vs 60.0% | Bemitil plus standard care (n=23) vs standard care (n=25) · Author-reported p<0.05 |
| Circulating CD3+ T cells | 1.082 vs 0.631 × 10⁹/L | Bemitil vs standard care; healthy donor mean 1.122 × 10⁹/L · p<0.05 between treatment groups |
| Circulating CD4+ T cells | 0.687 vs 0.442 × 10⁹/L | Bemitil vs standard care · p<0.05 between treatment groups |
| Humoral measures | Lower circulating immune complexes | The author reports little difference in other humoral measures. |
Selected postoperative blood-cell measures (Table 3)
| Measure | Bemitil + care (n=23) | Standard care (n=25) | Healthy donors (n=37) |
|---|---|---|---|
| Lymphocytes, × 10⁹/L | 2.121 ± 0.04 | 1.144 ± 0.08 | 2.322 ± 0.04 |
| CD3+, × 10⁹/L | 1.082 ± 0.03 | 0.631 ± 0.04 | 1.122 ± 0.03 |
| CD4+, × 10⁹/L | 0.687 ± 0.04 | 0.442 ± 0.05 | 0.780 ± 0.04 |
| CD8+, × 10⁹/L | 0.480 ± 0.02 | 0.334 ± 0.03 | 0.428 ± 0.01 |
Mean ± standard error as tabulated. The 37 donors served as a laboratory reference group.
Treatment assignment and outcome assessment are insufficiently described to estimate a causal clinical effect.
Source for these results ↗ · Reviewed 2026-11-10
For research and education. Consult a qualified clinician for medical advice.
Study limitations and source details
Study limitations
- The source does not describe randomized allocation or blinded outcome assessment.
- The published percentage and significance label are the author’s reported values. The full clinical outcome figure and statistical procedure could not be verified from the transcription.
Source access
Russian author-abstract transcription, methods, Table 3 and Figure 4 description checked.
Source reviewed 2026-11-10.
Source type: Dissertation author abstract
Citation and original source
Original source: O. V. Maslova. Bemitil after surgery for lung abscesses Chelyabinsk State Medical Academy. Dissertation author abstract, 2004. 2004.
Molekul research summary: https://molekul.io/research/bemitil-maslova-lung-abscess-2004. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry