Research libraryMOLEKUL / SOURCE RECORD

Investigation of Bemethyl Biotransformation Pathways by Combination of LC–MS/HRMS and In Silico Methods

D. A. Belinskaia, E. I. Savelieva, G. V. Karakashev, O. I. Orlova, M. A. Leninskii, N. S. Khlebnikova, N. N. Shestakova, A. R. Kiskina · 2021 · Int J Mol Sci. 22(16):9021. PMID 34445727

Analytical / composition studyEnglish abstractSource linked

This is Molekul’s research summary, not the original publication. Educational information only, not medical advice. Seek qualified healthcare help for medical conditions.

What does this source report?

Identifies nine metabolites with six molecular formulas in rat urine and proposes biotransformation pathways involving glutathione conjugation.

Population and setting: Rat urine, mass spectrometry and computational metabolism / docking models
Evidence type: Analytical / composition study
Preparation: See the original report; formulation details require verification.
Source language: Russian
Title provenance: Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

Rat metabolite identification and docking do not establish human efficacy, detoxification benefit or clinical interactions.
Full-text host was located; this entry was appraised from the indexed abstract.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Indexed citation and abstract checked; full methods and risk of bias remain unreviewed.

Recorded source-check date: 2026-09-29. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.3390/ijms22169021

Cite and trace this record

Original source: D. A. Belinskaia, E. I. Savelieva, G. V. Karakashev, O. I. Orlova, M. A. Leninskii, N. S. Khlebnikova, N. N. Shestakova, A. R. Kiskina. Investigation of Bemethyl Biotransformation Pathways by Combination of LC–MS/HRMS and In Silico Methods Int J Mol Sci. 22(16):9021. PMID 34445727 2021.

Molekul research summary: https://molekul.io/research/acto-34445727. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

Bemitil

A benzimidazole-derived actoprotector, also indexed as bemethyl and Metaprot. Research spans patient asthenia, occupational settings, neuromuscular and liver studies, metabolism and preclinical safety; these are research contexts, not established uses.

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