Bemethyl and cytochrome P450: rat liver and human lymphocytes
E. A. Sorokina, S. V. Sibiriak, S. A. Sergeeva · 2002 · Eksp Klin Farmakol. 65(3):31–34. PMID 12227093
What does this source report?
Reports mixed-type hepatic enzyme induction in rats and concentration-dependent enzyme-activity changes in cultured human lymphocytes.
- Population and setting
- Rat liver after administration; human lymphocytes in vitro
- Evidence type
- Animal / experimental
- Preparation
- See the original report; formulation details require verification.
- Source language
- Russian
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- The indexed English title says human liver, but the abstract identifies rat liver and human cells in vitro.
- This raises an interaction-research question, not a validated list of human drug interactions.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed citation and abstract checked; full methods and risk of bias remain unreviewed.
Recorded source-check date: 2026-09-29. This date does not imply a completed systematic review.
Cite and trace this record
Original source: E. A. Sorokina, S. V. Sibiriak, S. A. Sergeeva. Bemethyl and cytochrome P450: rat liver and human lymphocytes Eksp Klin Farmakol. 65(3):31–34. PMID 12227093 2002.
Molekul research summary: https://molekul.io/research/acto-12227093. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry