Effect of bemethyl on the glutathione system in the rat liver in acute hypoxia
I. V. Zarubina, O. P. Mironova · 2002 · Eksp Klin Farmakol. 65(3):28–30. PMID 12227091
What does this source report?
Reports preservation of glutathione-related measures and enzyme activities. Actinomycin D inhibition experiments implicate an RNA-dependent process.
- Population and setting
- Rats in a pressure-chamber hypoxia model
- Evidence type
- Animal / experimental
- Preparation
- See the original report; formulation details require verification.
- Source language
- Russian
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Actinomycin D inhibits transcription; this does not by itself isolate a specific protein-synthesis pathway.
- Liver biochemical measures in rats do not establish treatment of human liver disease or altitude safety.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed citation and abstract checked; full methods and risk of bias remain unreviewed.
Recorded source-check date: 2026-09-29. This date does not imply a completed systematic review.
Cite and trace this record
Original source: I. V. Zarubina, O. P. Mironova. Effect of bemethyl on the glutathione system in the rat liver in acute hypoxia Eksp Klin Farmakol. 65(3):28–30. PMID 12227091 2002.
Molekul research summary: https://molekul.io/research/acto-12227091. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry