COMPOUND RECORD / UEQ-12-1

Ueq 12-1Пептид Ueq 12-1

Recovery

Source linked

Research profile Published findings and original sources.

01 / OVERVIEW

What is it?

Research context

A 45-residue sea-anemone peptide with five disulfide bonds, studied for TRPA1 potentiation and experimental pain, inflammation and antibacterial effects.

Selected study findings

animal · 2017

Study of this preparation · Indexed abstract; full methods not assessed

Peptide structure, channel assays, bacterial tests and animal pain/inflammation experiments

Ueq 12-1 potentiated TRPA1 and showed analgesic/anti-inflammatory activity in vivo, alongside moderate antibacterial activity.

Limit: This source identifies TRPA1 potentiation, not ASIC3 inhibition. Experimental findings do not establish human benefit or safety.

New Disulfide-Stabilized Fold Provides Sea Anemone Peptide to Exhibit Both Antimicrobial and TRPA1 Potentiating Properties. ↗

Selected findings. Study-specific limitations and preparation details accompany each source.

Compound class: Marine peptide research
Research collection: Neuropeptide research · editorial grouping
Research institutions: No institutional affiliation recorded
Source review: Review dates and the material assessed are listed with each publication below.

02 / EVIDENCE DIMENSIONS

Evidence assessment

Human research: —No human intervention study established in this collection
Study methods: —Animal and/or laboratory experiments; see individual sources
Independent replication: —Independent replication not assessed
Source access: —Original publication records linked
Safety evidence: —Human dosing and clinical safety are not established

Evidence assessed by study design, replication, source access and safety reporting.

Research context, history and detailed findings

EVIDENCE REVIEW / 6 OCTOBER 2026

Outstanding review questions

Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.

No human intervention report has been identified among the linked records; unclassified archival leads may remain. Publication records can share participants. Source counts are not trial counts.

View the collection-wide research audit ↗

03 / SOURCE RECORDS

Linked sources

Explore the research map and unresolved leads ↗

2017 · New Disulfide-Stabilized Fold Provides Sea Anemone Peptide to Exhibit Both Antimicrobial and TRPA1 Potentiating Properties.

2017Animal / experimentalEnglish abstract

New Disulfide-Stabilized Fold Provides Sea Anemone Peptide to Exhibit Both Antimicrobial and TRPA1 Potentiating Properties.

Logashina YA, Solstad RG, Mineev KS, Korolkova YV, Mosharova IV, Dyachenko IA, Palikov VA, Palikova YA, Murashev AN, Arseniev AS, Kozlov SA, Stensvåg K, Haug T, Andreev YA · Toxins. 2017;9(5):154.

Ueq 12-1 potentiated TRPA1 and showed analgesic/anti-inflammatory activity in vivo, alongside moderate antibacterial activity.

Population / setting: Peptide structure, channel assays, bacterial tests and animal pain/inflammation experiments
What was checked: Primary publisher abstract checked; full methods and tables not appraised.

Limitations & review scope

This source identifies TRPA1 potentiation, not ASIC3 inhibition.
Experimental findings do not establish human benefit or safety.

Source checked 2026-10-11. See the review scope above for the material assessed.

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