Rumalon and cartilage-degrading enzymes in human osteoarthritic cartilage
E. Vignon, et al. · 1990 · Clinical Rheumatology 9(3), 383–388
Indexed 2026-11-12.
Reported findings and study design
Narrative findings; numerical extraction incomplete
Enzyme-activity assays compared the glycosaminoglycan–peptide complex with sodium salicylate and indomethacin.
Dose, route and schedule
Enzyme-activity assays compared the glycosaminoglycan–peptide complex with sodium salicylate and indomethacin.
Protocol source ↗ · Original indexed abstract
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Cartilage enzyme activity | The authors reported dose-dependent inhibition of collagenolytic and proteoglycanase activity, with no change in phospholipase A2 activity. |
This was an assay of excised tissue. The abstract does not quantify an effect on cartilage in treated patients.
Source for these results ↗ · Reviewed 2026-11-12
For research and education. Consult a qualified clinician for medical advice.
Study limitations and source details
Study limitations
- This was an assay of excised tissue. The abstract does not quantify an effect on cartilage in treated patients.
Source access
Original indexed abstract
Source reviewed 2026-11-12.
DOI: 10.1007/BF02114400
Citation and original source
Original source: E. Vignon, et al.. Rumalon and cartilage-degrading enzymes in human osteoarthritic cartilage Clinical Rheumatology 9(3), 383–388 1990.
Molekul research summary: https://molekul.io/research/rumalon-vignon-1990. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry