Cytoprotective Effect of Peptide Sedatin, an Agonist of μ/δ-Opioid Receptors, on Primary Culture of Pulmonary Fibroblasts of Albino Rats under Conditions of Oxidative Stress.

What does this source report?

Sedatin preserved selected oxidative-stress and nuclear measures in rat pulmonary fibroblasts. Naloxone partially reduced these effects, supporting opioid involvement in this assay.

Population and setting

Primary rat pulmonary fibroblasts

Evidence type

In vitro

Preparation

See the original report; formulation details require verification.

Source language

English indexed abstract; original language: eng

Title provenance

Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

• Preclinical findings do not establish human benefit or safety.
• Indexed abstract reviewed; full methods and independent replication require appraisal.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Review depth: Abstract reviewed

Source access and review scope

Primary publication metadata and indexed abstract checked via Europe PMC; full methodological review pending.

Recorded source-check date: 2026-10-05. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1007/s10517-016-3340-3

Cite and trace this record

Original source: Sazonova EN, Samarina EY, Lebed'ko OA, Maltseva IM, Timoshin SS. Cytoprotective Effect of Peptide Sedatin, an Agonist of μ/δ-Opioid Receptors, on Primary Culture of Pulmonary Fibroblasts of Albino Rats under Conditions of Oxidative Stress. Bulletin of experimental biology and medicine 2016.

Molekul research summary: https://molekul.io/research/rp-27265138. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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