Research libraryMOLEKUL / SOURCE RECORD

Neuropeptide Cycloprolylglycine Exhibits Neuroprotective Activity after Systemic Administration to Rats with Modeled Incomplete Global Ischemia and in In Vitro Modeled Glutamate Neurotoxicity.

Povarnina PY, Kolyasnikova KN, Nikolaev SV, Antipova TA, Gudasheva TA · 2016 · Bulletin of experimental biology and medicine

Animal / experimentalEnglish abstractSource linked

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What does this source report?

CPG improved selected neurological and locomotor measures after incomplete global ischemia in rats and protected HT-22 cells against glutamate toxicity.

Population and setting: Rat ischemia model and HT-22 cells
Evidence type: Animal / experimental
Preparation: See the original report; formulation details require verification.
Source language: English indexed abstract; original language: eng
Title provenance: Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

Preclinical findings do not establish human benefit or safety.
Indexed abstract reviewed; full methods and independent replication require appraisal.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Review depth: Abstract reviewed

Source access and review scope

Primary publication metadata and indexed abstract checked via Europe PMC; full methodological review pending.

Recorded source-check date: 2026-10-05. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1007/s10517-016-3241-5

Cite and trace this record

Original source: Povarnina PY, Kolyasnikova KN, Nikolaev SV, Antipova TA, Gudasheva TA. Neuropeptide Cycloprolylglycine Exhibits Neuroprotective Activity after Systemic Administration to Rats with Modeled Incomplete Global Ischemia and in In Vitro Modeled Glutamate Neurotoxicity. Bulletin of experimental biology and medicine 2016.

Molekul research summary: https://molekul.io/research/rp-27021093. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

CPG & GZK-111

A grouped record for endogenous cyclo(Pro-Gly), its experimental linear precursor GZK-111 and the connection to Noopept metabolism.

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