Pyroglutamyl-asparagine amide normalizes long-term potentiation in rat hippocampal slices.

Kapai NA, Chepkova AN, Gudasheva TA, Morozova AA, Skrebitskii VG · 2004 · Bulletin of experimental biology and medicine

In vitroEnglish abstractSource linked

This is Molekul’s research summary, not the original publication. Educational information only, not medical advice. Seek qualified healthcare help for medical conditions.

What does this source report?

Pyroglutamyl-asparagine amide facilitated weakly induced long-term potentiation and countered ethanol-impaired potentiation in rat hippocampal slices. This separate piracetam-inspired dipeptide is not CPG.

Population and setting: Rat hippocampal slices
Evidence type: In vitro
Preparation: See the original report; formulation details require verification.
Source language: English indexed abstract; original language: eng
Title provenance: Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

Preclinical findings do not establish human benefit or safety.
Indexed abstract reviewed; full methods and independent replication require appraisal.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Review depth: Abstract reviewed

Source access and review scope

Primary publication metadata and indexed abstract checked via Europe PMC; full methodological review pending.

Recorded source-check date: 2026-10-05. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1023/b:bebm.0000048374.18525.2e

Cite and trace this record

Original source: Kapai NA, Chepkova AN, Gudasheva TA, Morozova AA, Skrebitskii VG. Pyroglutamyl-asparagine amide normalizes long-term potentiation in rat hippocampal slices. Bulletin of experimental biology and medicine 2004.

Molekul research summary: https://molekul.io/research/rp-15662458. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

CPG & GZK-111

A grouped record for endogenous cyclo(Pro-Gly), its experimental linear precursor GZK-111 and the connection to Noopept metabolism.

Piracetam

Piracetam, marketed as Nootropil, connects the original nootropic concept with Soviet clinical adoption and later operator, hypoxia and maritime research. Healthy-volunteer experiments, clinical reviews and combination proposals answer different questions.

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