Research libraryMOLEKUL / SOURCE RECORD

Early placebo-controlled rintatolimod trial

Strayer DR et al. · 1994 · Clinical Infectious Diseases

Indexed 2026-11-12.

Randomized trialEnglish abstractSource linked

Reported findings and study design

Reported findings

Randomized multicenter double-blind comparison of IV poly(I)·poly(C12U) and placebo over 24 weeks.

Dose, route and schedule

Randomized multicenter double-blind comparison of IV poly(I)·poly(C12U) and placebo over 24 weeks.

Protocol source ↗ · Original article abstract

Results · Original article abstract
MeasureResultComparison, timing and statistics
Functional measuresThe paper reports differences favoring active treatment for Karnofsky performance (p<0.03), treadmill duration (p=0.01) and activities of daily living (p<0.04).

The historical CDC definition and secondary measures limit comparisons with current studies.

Source for these results ↗ · Reviewed 2026-11-12

For research and education. Consult a qualified clinician for medical advice.

Study limitations and source details

Study limitations

  • The historical CDC definition and secondary measures limit comparisons with current studies.

Source access

Randomized multicenter double-blind comparison of IV poly(I)·poly(C12U) and placebo over 24 weeks.

Source reviewed 2026-11-12.

Open source ↗

Citation and original source

Original source: Strayer DR et al.. Early placebo-controlled rintatolimod trial Clinical Infectious Diseases 1994.

Molekul research summary: https://molekul.io/research/rintatolimod-amp-1994. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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