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Treatment of asthenic syndrome in chronic brain ischemia: TRIUMPH observational programme

A. I. Fedin, E. Yu. Solovyeva, O. P. Mironova, A. V. Fedotova · 2014 · Zh Nevrol Psikhiatr Im S S Korsakova. 114(12):104–111

Uncontrolled human reportFull text availableSource linked

This is Molekul’s research summary, not the original publication. Educational information only, not medical advice. Seek qualified healthcare help for medical conditions.

What does this source report?

The observational programme reported improved asthenia scores. Treatment duration was selected by physicians, not randomly assigned.

Population and setting: 2,029 participants; 1,170 analyzed; 859 excluded for protocol completion/documentation problems
Evidence type: Uncontrolled human report
Preparation: See the original report; formulation details require verification.
Source language: Russian unless otherwise indicated
Title provenance: Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

Large exclusion from analysis creates potential selection bias.
No untreated control; within-person improvement cannot establish causation.
This programme is not a randomized trial and cannot establish long-term safety.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Document format: Publisher HTML article

Review depth: Methods and analysis-population narrative

Source access and review scope

Publisher methods and analysis-population passage checked.

Recorded source-check date: 2026-10-02. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.17116/jnevro2014114121104-111

Cite and trace this record

Original source: A. I. Fedin, E. Yu. Solovyeva, O. P. Mironova, A. V. Fedotova. Treatment of asthenic syndrome in chronic brain ischemia: TRIUMPH observational programme Zh Nevrol Psikhiatr Im S S Korsakova. 114(12):104–111 2014.

Molekul research summary: https://molekul.io/research/phenotropil-triumph-2014. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

Phenotropil

A phenyl-substituted piracetam analogue connecting early Soviet experimental pharmacology, IMBP development and later clinical studies. Temperature-dependent animal findings, patient trials and healthy-volunteer PK studies address different questions.

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