Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank.
Mukhina AY, Mishina ES, Bobyntsev II, Medvedeva OA, Svishcheva MV, Kalutskii PV, Andreeva LA, Myasoedov NF · 2020 · Bulletin of experimental biology and medicine
Reported findings and study design
Male Wistar rats with restraint stress; IP Selank 80, 250 or 750 micrograms/kg 15 minutes before exposure.
Dose, route and schedule
Intraperitoneal doses of 80, 250 or 750 micrograms/kg, 15 minutes before stress exposure.
Protocol source ↗ · Indexed abstract
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Corticosterone and colon-wall injury | Reductions reported | No numerical concentration, injury score or sample size supplied |
Values describe this study and its comparison. Unreported effect sizes and missing denominators have not been inferred.
Source for the extracted data ↗ · Checked 2026-10-29
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Animal and laboratory findings do not establish benefit in people.
- Indexed abstract reviewed; complete methods, sample-size details and adverse-event tables have not been assessed.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Indexed abstract checked
Source access and review scope
Publication metadata and indexed abstract checked through Europe PMC on 28 October 2026; full text not appraised.
Recorded source-check date: 2026-10-28. This date does not imply a completed systematic review.
Citation and original source
Original source: Mukhina AY, Mishina ES, Bobyntsev II, Medvedeva OA, Svishcheva MV, Kalutskii PV, Andreeva LA, Myasoedov NF. Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank. Bulletin of experimental biology and medicine 2020.
Molekul research summary: https://molekul.io/research/oct28-32651826. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry