Dalargin plus carbohydrate loading during oropharyngeal cancer surgery
D. N. Vasiliev, D. E. Kulbakin, E. L. Choynzonov, S. V. Avdeev, A. A. Lee, I. P. Puteev, A. V. Pak, A. V. Kushner · 2025 · Siberian Journal of Oncology. 2025;24(1):29–38
Reported findings and study design
Narrative findings; numerical extraction incomplete
The combined protocol was associated with lower stress-hormone responses, more favorable aerobic-metabolism measures and fewer postoperative complications. The checked abstract does not quantify those outcome differences.
58 surgical patients with oropharyngeal cancer; 29 combined-intervention and 29 standard-care patients
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Stress-hormone response and metabolism | Lower stress-hormone release and more favorable aerobic-metabolism measures reported with the combined protocol | Dalargin plus carbohydrate loading versus standard perioperative care; numerical changes not available in the checked abstract · Perioperative assessments |
| Postoperative complications | Fewer complications reported; counts, types and effect uncertainty not extracted | No numerical risk reduction inferred |
| Study groups | 29 combined-intervention versus 29 standard-care patients; 58 total |
A combined perioperative intervention, not isolated Dalargin efficacy or an anticancer trial. Reported differences remain qualitative until outcome tables can be checked.
Source for the extracted data ↗ · Checked 2026-11-06
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Dalargin was combined with carbohydrate loading; the independent contribution of each is unresolved.
- Randomization, masking and allocation concealment were not established in the checked abstract.
- Numerical complication counts, effect sizes and uncertainty require the original outcome tables.
- Perioperative metabolic findings do not demonstrate improved tumor control or cancer survival.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original publisher abstract in journal PDF
Review depth: Publisher abstract checked; numerical outcome tables not yet extracted
Source access and review scope
Original journal abstract; no complete risk-of-bias appraisal or verification of full outcome tables.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Original clinical journal publication
Citation and original source
Original source: D. N. Vasiliev, D. E. Kulbakin, E. L. Choynzonov, S. V. Avdeev, A. A. Lee, I. P. Puteev, A. V. Pak, A. V. Kushner. Dalargin plus carbohydrate loading during oropharyngeal cancer surgery Siberian Journal of Oncology. 2025;24(1):29–38 2025.
Molekul research summary: https://molekul.io/research/dalargin-perioperative-metabolism-2025. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry