Dexamethasone and vitamin B(12) synergistically promote peripheral nerve regeneration in rats by upregulating the expression of brain-derived neurotrophic factor.
Sun H, Yang T, Li Q, Zhu Z, Wang L, Bai G, Li D, Li Q, Wang W · 2012 · Archives of medical science : AMS
What does this source report?
B12 and dexamethasone experiments report functional, electrophysiological and myelinated-fiber changes alongside increased BDNF expression.
- Population and setting
- 96 male Wistar rats with sciatic-nerve injury
- Evidence type
- Animal / experimental
- Preparation
- Vitamin B12 with or without dexamethasone; not Binavit
- Source language
- Russian or indexed English translation; see original
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Animal combination research does not establish human nerve repair or a Binavit effect. This international study supplies mechanistic context, not Soviet provenance.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed citation and abstract checked; complete methods and risk-of-bias appraisal pending.
Recorded source-check date: 2026-09-30. This date does not imply a completed systematic review.
Source provenance: Journal publication
Cite and trace this record
Original source: Sun H, Yang T, Li Q, Zhu Z, Wang L, Bai G, Li D, Li Q, Wang W. Dexamethasone and vitamin B(12) synergistically promote peripheral nerve regeneration in rats by upregulating the expression of brain-derived neurotrophic factor. Archives of medical science : AMS 2012.
Molekul research summary: https://molekul.io/research/bin-23185205. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry