Administration of Myelin Basic Protein Peptides Encapsulated in Mannosylated Liposomes Normalizes Level of Serum TNF-α and IL-2 and Chemoattractants CCL2 and CCL4 in Multiple Sclerosis Patients
Y. Lomakin, A. Belogurov, I. Glagoleva, A. Stepanov, K. Zakharov, J. Okunola, I. Smirnov, D. Genkin, A. Gabibov · 2016 · Mediators of Inflammation. 2016:2847232
Study data at a glance
- Participants or experimental model
- Biomarker analysis from the same Phase I Xemys research program
- Reported results
- The paper reports changes in circulating cytokines and chemokines after Xemys exposure.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Same clinical program as the Phase I report; not an independent efficacy trial.
- Biomarker changes do not demonstrate restored immune tolerance or clinical disease modification.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Related-report group: xemys-fasems-2013-2014. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original publisher summary checked; linked full text available.
Recorded source-check date: 2026-11-05. This date does not imply a completed systematic review.
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DOI: 10.1155/2016/2847232
Citation and original source
Original source: Y. Lomakin, A. Belogurov, I. Glagoleva, A. Stepanov, K. Zakharov, J. Okunola, I. Smirnov, D. Genkin, A. Gabibov. Administration of Myelin Basic Protein Peptides Encapsulated in Mannosylated Liposomes Normalizes Level of Serum TNF-α and IL-2 and Chemoattractants CCL2 and CCL4 in Multiple Sclerosis Patients Mediators of Inflammation. 2016:2847232 2016.
Molekul research summary: https://molekul.io/research/auto-xemys-cytokines-2016. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry