Synthetic peptide TEKKRRETVEREKE derived from ezrin induces differentiation of NIH/3T3 fibroblasts.
Chulkina M, Negmadjanov U, Lebedeva E, Pichugin A, Mazurov D, Ataullakhanov R, Holmuhamedov E · 2017 · European journal of pharmacology · PMID 28668507
What does this source report?
The defined TEKKRRETVEREKE peptide promoted differentiation-related changes through ERK1/2 signaling without SMAD activation.
- Population and setting
- NIH/3T3 mouse fibroblasts, including CD44-knockout cells
- Evidence type
- In vitro
- Preparation
- See the original report; formulation details require verification.
- Source language
- English indexed abstract; original language:
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Cell signaling does not quantify wound healing in patients.
- Full methods, reporting completeness and independent replication remain to be appraised.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Abstract reviewed
Source access and review scope
Primary citation and indexed abstract reviewed through Europe PMC. Full article not appraised.
Recorded source-check date: 2026-10-05. This date does not imply a completed systematic review.
Source provenance: Original journal report
Cite and trace this record
Original source: Chulkina M, Negmadjanov U, Lebedeva E, Pichugin A, Mazurov D, Ataullakhanov R, Holmuhamedov E. Synthetic peptide TEKKRRETVEREKE derived from ezrin induces differentiation of NIH/3T3 fibroblasts. European journal of pharmacology · PMID 28668507 2017.
Molekul research summary: https://molekul.io/research/audit-28668507. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry