COMPOUND RECORD / PPC-M

PPC-MПБК-М

PerformanceStressRecovery

Source linked

01 / OVERVIEW

About PPC-M

Names in this research collection

PBK-M · Yamskova PPC-M

A bovine brain fraction with 2.18–7.76 kDa polypeptides and an albumin-like component. Characterization and rat injury observations are separate from PPK-V performance research.

Research background

A bovine brain fraction with 2.18–7.76 kDa polypeptides and an albumin-like component. Characterization and rat injury observations are separate from PPK-V performance research.

What the studies found

Animal research · 2026

Who or what was studied20 male Wistar rats across saline and PPC-M in the hemorrhage model, with separate in vitro and analytical assays.

Reported finding

PPC-M contained polypeptides in the 2,180–7,755 Da range and an albumin-like protein. Rat brain histology was described qualitatively.

Fraction 3H peptide masses: 2,180–7,755 DaMain text; conclusion prints 7,715 Da. Overlap by size with other extracts does not identify shared sequences.
Albumin-like component: Approximately 66.7 kDaN-terminal sequence was consistent with bovine serum albumin.
Histological observations: Ependymal cells, vascular structures and earlier wound-channel closure describedNo verified quantitative motor outcome or intact-peptide brain exposure.

All reported results & study design →

Methods, dose & source notes

Study of this preparation · Original article, sections 2.13 and 3; DOI 10.60797/IRJ.2026.164.62

Small animal comparison and descriptive histology. Printed concentration is unusually low and is retained as reported.

PPC-M bovine brain complex: analytical and rat histology study ↗

These highlights cover selected studies. Open a source for its methods, reported doses and full context.

Compound class: Bovine-brain peptide–protein complex
Research collection: Actoprotection & occupational pharmacology · editorial grouping
Research institutions: No institutional affiliation recorded
Source review: Review dates and the material assessed are listed with each publication below.

02 / HOW TO READ THE RESEARCH

Understanding the evidence

Human research No human study in the indexed paper.
Study methods MALDI-TOF, spectroscopy and exploratory rat histology.
Independent replication Independent replication is not established in the linked sources.
Source access Original sources and the exact review scope are linked below.
Safety evidence The linked experiments do not establish a safe human performance regimen.

Open a topic for the evidence assessment.

More findings, background and history

EVIDENCE REVIEW / 6 OCTOBER 2026

Outstanding review questions

Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.

No human intervention report has been identified among the linked records; unclassified archival leads may remain. Publication records can share participants. Source counts are not trial counts.

Browse original study records ↗

03 / SOURCE RECORDS

Linked sources

Explore the research map and unresolved leads ↗

2026 · PPC-M bovine brain complex: analytical and rat histology studyFraction 3H peptide masses: 2,180–7,755 Da

2026Animal / experimentalRussian source · see review scope

PPC-M bovine brain complex: analytical and rat histology study

· Original article, sections 2.13 and 3; DOI 10.60797/IRJ.2026.164.62

Format: Original article, sections 2.13 and 3; DOI 10.60797/IRJ.2026.164.62 · Reviewed: Reported methods, results and evidence limitations

V. P. Yamskova, M. S. Krasnov, P. A. Yelistratov, V. M. Chekova, E. V. Sidorskii, A. P. Ilina · Original article, sections 2.13 and 3; DOI 10.60797/IRJ.2026.164.62

PPC-M contained polypeptides in the 2,180–7,755 Da range and an albumin-like protein. Rat brain histology was described qualitatively.

Findings, study figures and available tables

Reported findings and study design

PPC-M contained polypeptides in the 2,180–7,755 Da range and an albumin-like protein. Rat brain histology was described qualitatively.

MALDI-TOF and N-terminal sequencing, spectroscopy, protein aggregation assays and histology after experimental intracerebral hemorrhage.

Dose, route and schedule

Daily intranasal 20 µL per nostril of saline or PPC-M at the printed concentration of 10⁻¹² mg protein/mL.

Protocol source ↗ · Original article, sections 2.13 and 3; DOI 10.60797/IRJ.2026.164.62

Reported findings and study figures · Original article, sections 2.13 and 3; DOI 10.60797/IRJ.2026.164.62
Measure	Result	Comparison, timing and statistics
Fraction 3H peptide masses	2,180–7,755 Da	Main text; conclusion prints 7,715 Da. Overlap by size with other extracts does not identify shared sequences.
Albumin-like component	Approximately 66.7 kDa	N-terminal sequence was consistent with bovine serum albumin.
Histological observations	Ependymal cells, vascular structures and earlier wound-channel closure described	No verified quantitative motor outcome or intact-peptide brain exposure.

Small animal comparison and descriptive histology. Printed concentration is unusually low and is retained as reported.

Source for the extracted data ↗ · Checked 2026-11-09

Population / setting: 20 male Wistar rats across saline and PPC-M in the hemorrhage model, with separate in vitro and analytical assays.
What was checked: Original article, sections 2.13 and 3; DOI 10.60797/IRJ.2026.164.62

Limitations & review scope

Small animal comparison and descriptive histology. Printed concentration is unusually low and is retained as reported.

Source checked 2026-11-09. See the review scope above for the material assessed.

Read the source ↗

Research collection curated by @PepMariner · editorial standards. Send a source correction ↗

Browse bibliography & PDFs ↗